Nike React Infinity Run Flyknit 4 Womens

With supportive cushioning built for a smooth run, the Nike InfinityRN 4 is a brand-new take on a familiar favourite. It's made from responsive foam cushioning designed to support a fresh, energetic ride. (What's more? Responsive foam cushioning is designed with a reduced-impact manufacturing approach for the midsole. The construction combines the responsive foam cushioning with Nike Running's best-fitting knitted upper yet, so you can feel confident in every stride with soft upper support and breathability. It's the kind of shoe that supports every step in style.

What's new about the Nike InfinityRN 4?

This version of the Nike InfinityRN 4 still provides a plush and smooth ride, with the new responsive foam cushioning delivering more support. The revamped knitted upper and wider toe box help your foot feel stable and secure.

Cushioning: super-high

The more cushioning that you have underfoot, the softer and more comfortable your running experience can be. Cushioning helps soften the impact as your feet hit the ground. Responsive foam cushioning gives you an incredibly smooth feeling, helping you push your limits.

Support: high

The more supportive the shoe, the more stability it can give to your natural stride. A combination of tuned support and intentionally placed cushioning helps you feel secure with every step. A curved outsole helps your foot rock smoothly from heel to toe and through your stride to footstrike. It makes every step feel more natural and adds efficiency to your run, helping you waste less energy as you hit your stride. A new internal knitted upper fit band (like a rubber band around the middle of your foot) offers elastic, secure support.

Responsiveness: moderate

The more responsive the shoe, the more energy return you can get back with each step. Whether you want to run a little bit faster or with a little less effort, responsive shoes help give you slightly more spring in your step to get more out of your run. Responsive foam cushioning supports an energetic feel during your run.

Contained breathability

A water-repellent liner in the toe helps keep you dry when the weather turns.

More benefits

• Waffle outsole provides durable traction.
• knitted upper tongue is adjustable and plush.
• Foam collar is soft and supportive to the touch.
• Increased rubber at the outsole gives traction and durability.
• B Width, Standard

Product details

• Weight: 281g (women's size 5.5)
• Heel-to-toe drop: 9mm
• Colour Shown: Black/Dark Grey/White

Size Guide

Tip: choose your usual size. For a looser fit, select half a size up.

Care Tips for Athletic & Everyday Shoes

To keep your shoes looking great and performing at their best, follow a few simple care guidelines. Proper care can help extend the life of your footwear while maintaining its comfort, shape, and appearance.

For Athletic & Running Shoes:

• Remove excess dirt and debris with a soft brush or cloth.
• Remove the laces and insoles before cleaning when possible.
• Clean gently with mild soap and lukewarm water.
• Avoid machine washing, as it can damage materials, cushioning, and adhesives.
• Never use bleach or harsh cleaning products.
• Air dry naturally at room temperature and avoid radiators, dryers, or direct heat.
• Stuff shoes with paper while drying to help maintain their shape.
• Avoid prolonged exposure to direct sunlight while drying.

For Everyday & Casual Shoes:

• Clean regularly to prevent dirt and stains from building up.
• Use a soft brush or cloth appropriate for the shoe material.
• Follow the manufacturer's care instructions for leather, suede, mesh, or synthetic materials.
• Use suitable protectors or water-repellent products when recommended for the material.
• Allow shoes to dry completely before wearing them again.
• Store them in a cool, dry place away from excessive moisture and heat.

Extra Tips:

• Rotate between pairs when possible to allow shoes to air out between wears.
• Store shoes in a well-ventilated area.
• Don't put damp shoes away in closed spaces.
• Avoid harsh chemicals and aggressive scrubbing that can damage the materials.

At OurTread, we select footwear designed with quality materials and thoughtful construction to deliver comfort, durability, and dependable performance. From breathable uppers and lightweight cushioning to durable outsole compounds, each shoe is designed to support comfortable movement and everyday performance.

Material composition and construction vary by brand and model. For specific details, please refer to the product specifications provided for each shoe.

Note: OurTread maintains an independent sourcing and product-review process. Before dispatch, each item is checked to confirm that it matches the specifications, condition, sizing, and details presented on the product page.